Degos disease, also known as Köhlmeier-Degos disease or malignant atrophic papulosis, is an extremely rare condition caused by blockage of arteries and veins. Individuals with this condition will develop papules. Degos disease, an ultra-rare disease, often shows skin lesions with a unique look—white centers surrounded by red rim.
In some cases, it can spread to other organs like the stomach or brain, leading to serious complications if not treated properly and quickly. Degos disease can be broadly categorized as a vasculopathy or an endovasculitis. It is an occlusive arteriopathy involving small-caliber vessels. Specifically, it causes progressive occlusion...
degos disease, Degos disease, also known as malignant atrophic papulosis or Köhlmeier-Degos disease, is a progressive and often lethal obliterative vasculopathy that affects the skin, gastrointestinal tract, and central nervous system. It was first described by French dermatologist Dr. Robert Degos in 1942. This article aims to explain Degos disease, detailing how it impacts the body, how it is diagnosed, and the current approaches to its management. Degos disease, also known as malignant atrophic papulosis (MAP) or Köhlmeier’s Degos disease, is a rare vasculopathy.
degos disease, Some individuals with Degos disease have isolated skin involvement and develop porcelain-white macules on their skin. Other individuals have more wide spread disease. Degos disease, also known as malignant atrophic papulosis, is an often-fatal disorder characterized by multiple infarcts in the skin and viscera owing to a thrombotic vasculopathy of unknown cause. Altered platelet function or fibrinolysis have been noted in some patients. Malignant atrophic papulosis is generally regarded as a serious vascular disease because it leads to the involvement of multiple organs and results in death within 2–3 years.
