Orthokeratosis - Health Inspiration

Orthokeratosis ... Orthokeratosis is hyperkeratosis without parakeratosis. No nucleus is seen in the cells.

There is also formation of an anuclear keratin layer, [1] as in the normal epidermis. Orthokeratosis is the normal ‘basket weave’ appearance of the stratum corneum seen in normal skin. In acral skin (palms or soles), the stratum corneum exhibits thickening and compaction ('compact orthokeratosis'). The orthokeratosis pattern is subdivided into plexiform orthokeratosis (e.g.

orthokeratosis, in normal skin, apart from inguinal skin), compact orthokeratosis (e.g. in lichen planus or lichen simplex chronicus vidal) or lamellar orthokeratosis (e.g. in ichthyosis vulgaris, autosomal dominant). Orthokeratosis is a condition characterized by an increase in the thickness of the horny layer (stratum corneum) due to the presence of normal appearing, anucleate cells. MedGen UID: 816058 Concept ID: C3809728 Disease or Syndrome Synonym: Alternating orthokeratosis and parakeratosis