Tricyclics - Health Inspiration

Patients taking an older class of antidepressant medications, known as tricyclics, face an elevated risk of heart disease, according to a study published in the European Heart Journal. But the same ... Tricyclics are a class of antidepressant medications that are sometimes used in the treatment and managment of depression.

They affect neurotransmitter pathways throughout the body, including serotonin and norepinephrine. Tricyclic drugs work by increasing the brain's supply of norepinephrine and serotonin levels - chemicals that are often abnormally low in depressed patients. Unlike some other antidepressants, tricyclics do not act by stimulating the central nervous system or by blocking monoamine oxidase.